Focal Accumulation of Iron in Cerebral Regions in Early ALS (Amyotrophic Lateral Sclerosis) Patients
Status:
Completed
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
The FAIR-ALS study is to investigate the safety and efficacy of a scavenger treatment of iron
deferiprone, which would reduce the brain iron to limit the development of amyotrophic
lateral sclerosis.
It has been shown an excess of iron in the central nervous system carrying a sporadic ALS
patients. Iron overload associated with a loss of motor neurons may explain the signs of the
disease (atrophy).
The investigators discuss the hypothesis that reducing excess iron, the investigators can
reduce the loss of neurons and thus the progression of signs of the disease.