Folate and Protection Against Cervical Cancer

• Status: Terminated
• Trial end date: 2007-05-01
• Target enrollment: 0
• Participant gender: Female

Summary

This is a randomised double-blind placebo-controlled trial to see whether giving a low dose of the vitamins folic acid and riboflavin is beneficial to women who have very low grade abnormalities of the cervical cells.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust
• Collaborator: World Cancer Research Fund International
• Treatments: Folic Acid; Riboflavin; Vitamin B Complex

Criteria

Inclusion Criteria:

• biopsy-diagnosed CIN1 infection with oncogenic HPV

Exclusion Criteria:

Any other stage of cervical abnormality pregnant or planning a pregnancy diabetic taking B vitamin supplements taking anti-epileptic treatment taking methotrexate bleeding after intercourse abnormal GI function infection with chlamydia, HIV or other agent