Four Interventions in the Management of Psychomotor Agitation, Safety and Efficacy Evaluation
Status:
Completed
Trial end date:
2011-03-01
Target enrollment:
Participant gender:
Summary
This study aims to evaluate the efficacy and safety of four options of medications in the
management of acute psychomotor agitation,or violence and aggression situations in health
services. All of the treatment options are already approved and currently used for this
purpose. The options are: haloperidol plus midazolam, haloperidol plus promethazine,
olanzapine and ziprasidone. The investigators hypothesized that all treatment options are
effective in the treatment of acute agitation, but the combination haloperidol plus
promethazine could elicit more adverse affects than the others.