Fractional Laser Assisted Delivery of Anesthetics

• Status: Completed
• Trial end date: 2014-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to assess the efficacy of fractional CO2 laser assisted delivery of topically applied anesthetics (articaine hydrochloride 40 mg/ml and epinephrine 10 μg/ml solution and EMLA cream) regarding to anesthesia of the skin.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Netherlands Institute for Pigment Disorders
• Collaborator: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
• Treatments: Anesthetics; Carticaine; EMLA; Epinephrine; Epinephryl borate; Lidocaine; Lidocaine, Prilocaine Drug Combination; Prilocaine; Racepinephrine

Criteria

Inclusion Criteria:

• Fitzpatrick skin type I or II

• Age ≥18 years

• Patient is willing and able to give written informed consent

Exclusion Criteria:

• History of keloid or hypertrophic scar formation or complicated wound healing

• Presence of any active skin disease

• Known allergy to local anesthesia

• Pregnancy or lactation

• Incompetency to understand what the procedure involves

• Current complaints of chronic pain or other alterations in pain sensation (e.g. due to diabetes mellitus or lepra)

• Current treatment with systemic analgesics or other medication that can influence pain sensation

• Current treatment with anticoagulants

• Fitzpatrick skin type III-VI

• Excessive sun tan