Overview
Frozen Platelets in the Treatmentof Traumatic or Vascular Bleeding
Status:
Not yet recruiting
Not yet recruiting
Trial end date:
2026-01-01
2026-01-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
Primarily due to its logistical advantages The Netherlands Armed Forces (NLAF) have been successfully using deep frozen (-80°C) platelets (DTC) for the treatment of (massive) bleeding trauma patients in austere environments since 2001. However, high-quality evidence for effectiveness and safety in the treatment of these type of patients is currently lacking. The MAssive transfusion of Frozen bloOD (MAFOD) trial is therefore designed to compare the haemostatic effect of DTCs versus room temperature stored platelets (RSP) in the treatment of trauma- and vascular bleeding.Phase:
Phase 3Accepts Healthy Volunteers?
NoDetails
Lead Sponsor:
Alrijne Ziekenhuis LeiderdorpCollaborator:
Erasmus Medical Center
Criteria
Inclusion Criteria:- Patients of 12 years or older
- Alive at hospital presentation
- Requiring massive transfusion including platelets
- Signed (deferred) consent
Exclusion Criteria:
- Known pregnancy