Overview

Frozen Platelets in the Treatmentof Traumatic or Vascular Bleeding

Status:
Not yet recruiting
Trial end date:
2026-01-01
Target enrollment:
0
Participant gender:
All
Summary
Primarily due to its logistical advantages The Netherlands Armed Forces (NLAF) have been successfully using deep frozen (-80°C) platelets (DTC) for the treatment of (massive) bleeding trauma patients in austere environments since 2001. However, high-quality evidence for effectiveness and safety in the treatment of these type of patients is currently lacking. The MAssive transfusion of Frozen bloOD (MAFOD) trial is therefore designed to compare the haemostatic effect of DTCs versus room temperature stored platelets (RSP) in the treatment of trauma- and vascular bleeding.
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Alrijne Ziekenhuis Leiderdorp
Collaborator:
Erasmus Medical Center
Criteria
Inclusion Criteria:

- Patients of 12 years or older

- Alive at hospital presentation

- Requiring massive transfusion including platelets

- Signed (deferred) consent

Exclusion Criteria:

- Known pregnancy