Functional Magnetic Resonance Imaging of ATP Cough in Chronic Cough Patients
Status:
Recruiting
Trial end date:
2021-07-30
Target enrollment:
Participant gender:
Summary
Persistent cough is a distressing symptom for people with respiratory disorders. Patients
also often experience an ongoing urge-to-cough that prompts coughing, and which fails to
resolve the sensation. Understanding how the brain controls cough and the urge-to-cough could
lead to new cough suppressing therapies. The overall objective of this project is to use
functional brain imaging (fMRI) to identify brain regions that are involved in the
exaggerated urge-to-cough in humans with chronic cough. Our focus will be on the brainstem
where information from the airways first arrives in the central nervous system.
Phase:
N/A
Details
Lead Sponsor:
Stuart Mazzone
Collaborators:
Imperial College London Monash University Queen's University, Belfast