Furoscix in Heart Failure Patients With Diuretic Resistance
Status:
Not yet recruiting
Trial end date:
2023-08-01
Target enrollment:
Participant gender:
Summary
This will be a randomized, open-label pilot study of 60 patients with and without diuretic
resistance who were recently admitted and discharged for acute decompensated heart failure
with and oral furosemide regimen testing whether Furoscix is more effective at achieving
post-discharge outpatient diuresis than standard of care. Diuretic resistance will be
identified using the BAN-ADHF (BUN, creAtinine, NP-levels, Age, Diabetes and DBP, HF
hospitalization, and atrial Fibrillation) score which has been integrated into the electronic
health record. The score is integer-based with a score of > 11 indicating diuretic resistance
with high likelihood of poor outcomes. The primary outcome is spot urine sodium at 1 hour, 4
hours, and 8 hours post-treatment.