Furosemide Stress Test as a Predictor of Tubular Function in Chronic Kidney Disease
Status:
Unknown status
Trial end date:
2017-04-01
Target enrollment:
Participant gender:
Summary
In kidney diseases, tubule-interstitium has become much more relevant, as formerly only the
glomerulus was considered to have the main importance. Kidney's tubular atrophy and
interstitital fibrosis is now recognized as long term prognostic value. We aim to evaluate
the function of the kidney's tubule-interstitium through furosemide excretion after
intravenous administration of this drug, and correlate the rate of excretion of furosemide
with interstitial fibrosis findings in scheduled kidney biopsy for patients with chronic
kidney disease.