Overview

GVAX Pancreas Vaccine (With CY) and CRS-207 With or Without Nivolumab

Status:
Completed
Trial end date:
2017-07-21
Target enrollment:
Participant gender:
Summary
The primary objective of this study is to compare the overall survival (OS) of subjects with previously treated metastatic pancreatic cancer treated with cyclophosphamide (CY)/nivolumab/GVAX pancreas vaccine followed by nivolumab/CRS-207 (Arm A) to subjects treated with CY/GVAX pancreas vaccine followed by CRS-207 (Arm B).
Phase:
Phase 2
Details
Lead Sponsor:
Sidney Kimmel Comprehensive Cancer Center
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Collaborators:
Aduro BioTech
Aduro Biotech, Inc.
American Association for Cancer Research
Bristol-Myers Squibb
Lustgarten Foundation
Stand Up To Cancer
Treatments:
Antibodies, Monoclonal
Cyclophosphamide
Nivolumab
Pancreatin
Pancrelipase
Vaccines