GW273225 Therapy Added To Current Seizure Treatments In Patients With Partial Seizures

• Status: Withdrawn
• Trial end date: 2008-03-01
• Target enrollment: 0
• Participant gender: All

Summary

Study to determine drug interactions between GW273225 and the anticonvulsants valproate, carbamazepine or phenytoin

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: GlaxoSmithKline

Criteria

Inclusion criteria:

• Confident diagnosis of epilepsy

• Currently on VPA, CBZ or PHT

• >or= 4 seizures/4 weeks prior to screen

Exclusion criteria:

• Prior lamotrigine use (excluded if treatment discontinued for clinically significant safety reasons (i.e., rash, hypersensitivity)).

• Females of childbearing potential on hormonal contraceptives or hormone replacement therapy.