Gabapentin for Postoperative Pain Management After Cardiac Surgery With Median Sternotomy
Status:
Unknown status
Trial end date:
2009-02-01
Target enrollment:
Participant gender:
Summary
In this study we will focus on the postoperative recovery. A successful postoperative
recovery should bring the patient to at least to the pre-surgical level. This can probably be
achieved by a multimodal approach where at least postoperative pain and PONV are managed.
The surgical injury results in immobilisation which again can result in impaired cardiac,
respiratory and musculoskeletal system. Pain relief is a prerequisite for mobilisation and an
early return to the pre-surgical level. The preferred drugs for postoperative pain management
are opioids. Although opioids are known to be an effective analgesia, they have a series of
side effects: nausea, vomiting, constipation, respiratory deficiency, delirium among others.
Gabapentin has been tested for post operative pain. Randomized Clinical Trials have reported
a significant better pain scores with Gabapentin in several studies -most of them restricted
to the postoperative period in the post-anaesthesia care unit in many different kind of
surgeries.
We want to test if Gabapentin can be used instead of opioids for treatment of postoperative
pain after heart surgery by median sternotomy.