Gabapentin for Relief of Immediate Postoperative Pain

• Status: Withdrawn
• Trial end date: 2020-04-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to use gabapentin as an additional or alternative treatment for short term pain control following cesarean delivery in order to reduce the use of opioid pain medication and improve overall pain control following surgery.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Indiana University
• Treatments: Gabapentin; gamma-Aminobutyric Acid

Criteria

Inclusion Criteria:

1. Pregnant women at least 18 years of age

2. Gestational age > or = to 30 weeks

3. Singleton gestation

4. Women undergoing a non-emergent cesarean delivery

5. Spinal anesthesia or combined spinal-epidural anesthesia utilized during cesarean

6. Ability to undergo the informed consent process in English

Exclusion Criteria:

1. Vertical skin incision

2. General anesthesia for cesarean

3. History of major depression or postpartum depression requiring medication

4. Chronic opiate use during pregnancy, defined as anyone who has taken an opioid or opioid replacement therapy in the 3 days prior to admission for delivery. This does not include opioids given for labor anesthesia.

5. Magnesium sulfate treatment postpartum

6. Preexisting fibromyalgia, chronic pain syndrome, or rheumatologic disorder