Gabapentin on Postoperative Pain Associated With Ureteroscopy and Stents Insertion

• Status: Recruiting
• Trial end date: 2023-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The study's objective is to determine the efficacy of preoperative gabapentin in relieving postoperative pain, reducing opioid use and improving quality of recovery in subjects undergoing urologic surgery.

Investigators hypothesize that subjects receiving gabapentin will have lower pain scores, less opioid consumption and better quality of recovery as compared to subjects who are given a placebo.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Northwestern University
• Treatments: Gabapentin; gamma-Aminobutyric Acid

Criteria

Inclusion Criteria:

• Age 18 years to 75 years

• Patients with obstructive kidney stones undergoing elective ureteroscopy or cystoscopy with Ureteral stent placement

Exclusion Criteria:

• Age less than 18 or more than 75 years

• Acetaminophen allergy

• Gabapentin allergy

• Hydromorphone allergy

• Chronic use of gabapentin

• History of chronic pain (Pain for > than 3 months)

• Chronic renal insufficiency (Creatinine > 1.3)

• Seizure disorder

• Psychiatric disorders (medically treated)

• Chronic use of anticonvulsants, antidepressants, antipsychotics (use > 3 months)

• Antacids ingested within 2 hours prior to surgery

• History of gastric or duodenal ulcer

• Pregnant or lactating

• Inability to communicate in English