Gadoxetate Enhanced Imaging Study to Detect Prostate Cancer
Status:
Completed
Trial end date:
2016-12-08
Target enrollment:
Participant gender:
Summary
Background:
- Prostate cancer is the most common cancer type among men. Some prostate cancers respond to
hormonal therapy. However, some cell characteristics of other prostate cancers cause it not
to respond as well to these therapies. Researchers want to see if gadoxetate, a contrast
agent used to help identify damaged liver tissue, can help tell these types of prostate
cancer apart. It may be able to identify if a man has a type of prostate cancer for which
hormone therapy may not work as well.
Objectives:
- To see if gadoxetate can help identify different types of prostate cancers during imaging
studies.
Eligibility:
- Men at least 18 years of age who have prostate cancer. Participants will be having surgery
to either remove the prostate or take tumor tissue samples.
Design:
- Participants will be screened with a physical exam and medical history. Blood samples
will be collected.
- Participants will have a magnetic resonance imaging (MRI) scan of the lower torso. They
will receive gadoxetate during the MRI scan.
- Participants who have surgery will have a sample of their tumor cells collected. Those
who have a biopsy will provide cells from this biopsy for study.
- Treatment will not be provided as part of this study.