Overview

Gait Analysis Following Knee Viscosupplementation

Status:
Completed

Trial end date:
2017-01-01

Target enrollment:
0

Participant gender:
All

Summary

This is a pilot, double-blind, randomised trial that investigates which gait parameters are more sensitive following a single bolus injection of hyaluronic acid with mannitol, hyaluronic acid with sorbitol, or saline placebo for knee osteoarthritis. Outcome measures are gait analysis through a inertial sensors (Physilog), Knee Society Score (KSS), University of California Los Angeles (UCLA) activity-scale and EuroQol 5Dimensions. Follow-up will be of 4 weeks.

Phase:

Phase 2/Phase 3

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Brigitte Jolles, MD

Treatments:

Hyaluronic Acid
Mannitol
Sorbitol

Criteria

Inclusion Criteria:

- diagnosis of primary knee OA Ahlbäck II-III and signed consent forms.

Exclusion Criteria:

- recent history of infection, diabetes, neurological impairment, chronic venous or
lymphatic stasis, pain medication of level 2 or 3, psychiatric conditions,
contraindications for HA joint injection and previous HA or steroid injections in the
last six months.