Overview

Gazyvaro and Low Dose Radiotherapy in Early Stage Follicular Lymphoma

Status:
Recruiting
Trial end date:
2024-05-01
Target enrollment:
Participant gender:
Summary
Combined modality approach using Obitunuzumab and involved site low dose irradiation in early stage nodal follicular lymphoma. Radiation dose will be adapted for low-responders. Primary Objective: Evaluation of the rate of metabolic CR after low-dose involved site radiotherapy in combination with Gazyvaro (Obinutuzumab) in early stage nodal follicular lymphoma in order to avoid conventional full dose IF radiotherapy. Secondary Objective: Efficacy and safety of a response adapted radiation dose treatment schedule.
Phase:
Phase 2
Details
Lead Sponsor:
Heidelberg University
Collaborator:
Roche Pharma AG
Treatments:
Obinutuzumab