Gefitinib and Combination Chemotherapy in Treating Patients With Advanced or Recurrent Colorectal Cancer
Status:
Terminated
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Phase II trial to study the effectiveness of combining gefitinib with fluorouracil,
leucovorin, and irinotecan in treating patients who have advanced or recurrent colorectal
cancer. Biological therapies such as gefitinib may stop the growth of tumor cells by blocking
the enzymes necessary for tumor cell growth. Drugs used in chemotherapy use different ways to
stop tumor cells from dividing so they stop growing or die. Combining gefitinib with
fluorouracil, leucovorin, and irinotecan may kill more tumor cells