Gemcitabine Hydrochloride, Cisplatin, and Nab-Paclitaxel in Treating Patients With Advanced or Metastatic Biliary Cancers
Status:
Completed
Trial end date:
2020-08-13
Target enrollment:
Participant gender:
Summary
This phase II trial studies how well gemcitabine hydrochloride, cisplatin, and nab-paclitaxel
(paclitaxel albumin-stabilized nanoparticle formulation) work in treating patients with
biliary cancers (which includes the gallbladder and bile ducts inside and outside the liver)
that have spread to other places in the body and usually cannot be cured or controlled with
treatment. Drugs used in chemotherapy, such as gemcitabine hydrochloride, cisplatin, and
paclitaxel albumin-stabilized nanoparticle formulation, work in different ways to stop the
growth of tumor cells, either by killing the cells, by stopping them from dividing, or by
stopping them from spreading. Giving more than one drug (combination chemotherapy) may kill
more tumor cells.