Overview

Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors

Status:
Unknown status

Trial end date:
1969-12-31

Target enrollment:

Participant gender:

Summary

RATIONALE: Drugs used in chemotherapy, such as gemcitabine, paclitaxel, ifosfamide, and cisplatin, work in different ways to stop tumor cells from dividing so they stop growing or die. Giving more than one drug (combination chemotherapy) may kill more tumor cells. PURPOSE: This phase I/II trial is studying the side effects and best dose of gemcitabine when given together with paclitaxel, ifosfamide, and cisplatin, and to see how well they work in treating patients with progressive or relapsed metastatic germ cell tumors.

Phase:

Phase 1/Phase 2

Details

Lead Sponsor:

University of Southampton

Collaborator:

University Hospital Southampton NHS Foundation Trust

Treatments:

Albumin-Bound Paclitaxel
Cisplatin
Gemcitabine
Ifosfamide
Isophosphamide mustard
Lenograstim
Paclitaxel