Gemcitabine With/Out Erlotinib in Unresectable Locally Advanced/Metastatic Pancreatic Cancer
Status:
Completed
Trial end date:
2009-02-10
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. Biological therapies such as erlotinib use different ways to
stimulate the immune system and stop cancer cells from growing. Combining chemotherapy and
biological therapy may kill more tumor cells. It is not yet known if gemcitabine is more
effective with or without erlotinib in treating pancreatic cancer.
PURPOSE: Randomized phase III trial to determine the effectiveness of gemcitabine with and
without erlotinib in treating patients who have unresectable locally advanced or metastatic
pancreatic cancer.