Gender Differences in Switching From Smoking Regular Cigarettes to E-Cigarettes

• Status: Not yet recruiting
• Trial end date: 2021-08-31
• Target enrollment: 0
• Participant gender: All

Summary

This trial studies potential differences between men and women when switching from the use of combustible cigarettes to the National Institute on Drug Abuse's Standard Research E-Cigarette (SREC). Studying the differences between men and women may increase understanding about the effects of switching from smoking regular cigarettes to electronic cigarettes.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: M.D. Anderson Cancer Center
• Collaborators: National Cancer Institute (NCI); National Institute on Drug Abuse (NIDA)
• Treatments: Nicotine

Criteria

Inclusion Criteria:

• Current smoker, defined as smoking 5 or more cigarettes per day during the past 30 days.

• Produce an expired carbon monoxide (CO) of 5 parts per million (ppm) or more.

• A stable address and working telephone.

• Able to follow verbal and written instructions in English and complete all aspects of the study as determined by principal investigator (PI).

• Interested in trying electronic cigarettes (ECs).

Exclusion Criteria:

• Use of electronic cigarettes on more than 2 days in the past 30 days.

• Meet criteria for current major depressive disorder or suicidality.

• Report more than once weekly use of tobacco products other than cigarettes during the past 30 days.

• Report recent (past 30 days) or planned (within the next 45 days) involvement in smoking cessation activities.

• Uncontrolled or unstable medical condition (e.g., uncontrolled hypertension, angina, diabetes).

• Evidence of cognitive deficits or instability that would preclude reliable study participation.

• Women who are pregnant, breastfeeding, or are not using an acceptable method of birth control (if capable of becoming pregnant).

• Considered by the investigator to be an unsuitable or unstable candidate (including but not limited to the following situations: planned absences from Houston area, or unwilling or unable to comply with study procedures).