Opioids are widely used for pain relief after major abdominal surgeries[1]. Sex differences
in the opioid analgesia have been reported and investigated in human subjects and animal
models In this study, effects of sex difference on response to opioid analgesics after
abdominal surgeries will be assessed regarding; analgesic duration (primary variable),
frequency of analgesic requirement, total opioid consumption, Opioid related complications
(respiratory depression, Nausea & vomiting, itching, over-sedation, delayed intestinal
motility).