Gene Expression Profiles and Metformin Efficacy in Type 2 Diabetes

• Status: Unknown status
• Trial end date: 2013-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Our general aim is to investigate whether messenger RNA (mRNA) and/or microRNA (miRNA) expression profiles in white blood cells, predict metformin monotherapy efficacy in patients with type 2 diabetes.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Casa Sollievo della Sofferenza IRCCS
• Collaborator: University Hospital, Catania
• Treatments: Metformin

Criteria

Inclusion Criteria:

• Type 2 diabetes (duration of diabetes of at least 2 years)

• age 40-70 yrs

• HbA1c > 6.4 < 9.0

Exclusion Criteria:

• insulin therapy

• contraindications to metformin use