Generalized Anxiety and Seroquel

• Status: Terminated
• Trial end date: 2013-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The 12 week clinical trial of Seroquel in Generalized Anxiety Disorder (GAD) patients will be combined with fMRI experiments.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Mclean Hospital
• Treatments: Quetiapine Fumarate

Criteria

Inclusion Criteria:

• Provision of written informed consent

• Fluency in English

• A diagnosis of GAD

• No pregnancy

• Right-handedness

• Psychotropic medication-free at the start of the study

Exclusion Criteria:

• Pregnancy or lactation

• Any current DSM-IV-TR Axis I disorder

• Any mental retardation or cognitive impairment that precludes informed consent

• Known intolerance or lack of response to quetiapine fumarate

• Substance or alcohol dependence at enrollment

• Participation in another drug trial within 4 weeks prior enrollment

• History of allergic reaction or hypersensitivity to Seroquel or Seroquel XR

• History of prior Seroquel or other antipsychotic agents use

• Contraindications to magnetic resonance imaging

• Treatment with an effective medication for GAD