Overview

Genetics and HIV-1 Protease Inhibitors

Status:
Completed
Trial end date:
2008-06-01
Target enrollment:
Participant gender:
Summary
This study evaluated the blood levels of atazanavir according to a genetic makeup for CYP3A5 (cytochrome P450 3A5, an enzyme that metabolizes atazanavir). The hypothesis was that people with a slow-metabolizing genotype would have higher blood levels of atazanavir compared to people with the normal metabolizing genotype.
Phase:
Phase 4
Details
Lead Sponsor:
University of Colorado, Denver
Collaborator:
National Institute of Allergy and Infectious Diseases (NIAID)
Treatments:
Atazanavir Sulfate
HIV Protease Inhibitors
Protease Inhibitors