Genicular Nerve Blocks for Anterior Cruciate Ligament Knee Surgery

• Status: Recruiting
• Trial end date: 2025-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this randomized controlled trial is to assess a new analgesia regimen that includes the addition of genicular never blocks to our current standard regimen of peripheral nerve blocks, which includes an adductor canal block (ACB) and interspace between the popliteal artery and capsule of the posterior knee block (IPACK). The main questions it aims to answer are:

1. Does addition of genicular nerve blocks to standard peripheral block regimen significantly reduce the mean opioid consumption by 33% in the first 24 hours?

2. Does genicular nerve blocks reduce NRS pain scores?

3. Does genicular nerve blocks facilitate earlier discharge?

4. Does genicular nerve blocks last longer than 24 hours?

5. Does genicular nerve blocks improve pain management?

Eligible patients are those undergoing an anterior cruciate ligament repair at the Hospital for Special Surgery and participants will be randomized to receive the intervention (genicular nerve block) or the standard of care.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospital for Special Surgery, New York
• Treatments: Bupivacaine; Dexamethasone

Criteria

Inclusion Criteria:

• Age 18 - 80

• English speaking

• American Society of Anesthesiologists (ASA) I - III

• BMI < 35

• Scheduled for ambulatory arthroscopic unilateral anterior cruciate ligament repair surgery with bone tendon bone autograft

Exclusion Criteria:

• History of chronic pain syndromes

• Chronic opioid use (daily morphine milligram equivalents > 30 mg for at least 3 months)

• Contraindication to peripheral nerve blocks

• Contraindication to neuraxial anesthesia

• History of peripheral neuropathy or pre-existing neurological deficits

• Psychiatric or cognitive disorder that prohibit patient from following study protocol

• Allergy to local anesthetic or study medications

• Multi-ligament surgery

• History of substance abuse

• Infection at the site of injection