Genistein and Endometrial Hyperplasia

• Status: Completed
• Trial end date: 2008-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

The aim of this study is to verify the anti-estrogenic activity of Genistein, on the "non atypical endometrial hyperplasia", in premenopausal women.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Messina
• Treatments: Genistein; Norethindrone; Norethindrone Acetate

Criteria

Inclusion Criteria:

• Premenopausal women

• Age > = 44 years

• Dysfunctional uterine bleeding

• No treatment with other hormonal drugs (estrogen, progesterone)

• No local or general pathology negatively influenced by administration of genistein or progesterone

• No intrauterine pathologies (polyps, myomas)

• A "non atypical endometrial hyperplasia", confirmed by hysteroscopy with biopsy and histological examination

Exclusion Criteria:

• All the other conditions