Genotype Guided Versus Conventional Approach in Selection of Oral P2Y12 Receptor Blocker in Chinese Patients Suffering From Acute Coronary Syndrome

• Status: Completed
• Trial end date: 2015-08-01
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to compare the outcome between genotype guided versus clinical guided approach in selection of oral P2Y12 receptor blocker in Chinese patients suffering from acute coronary syndrome.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The University of Hong Kong
• Treatments: Clopidogrel; Platelet Aggregation Inhibitors; Ticagrelor; Ticlopidine

Criteria

Inclusion Criteria:

• Age of 18 years or above

• Diagnosis of Acute Coronary Syndrome

• P2Y12 receptor blocker naïve and planning for a loading dose of P2Y12 receptor blocker

Exclusion Criteria:

• Chronic renal failure on dialysis or plan for dialysis within 1 year

• Serious hepatic disease

• Active bleeding disorder

• Contraindicated or allergic to Clopidogrel or ticagrelor

• History of intracranial bleeding

• Women who are pregnant or who are of childbearing potential who do not use adequate contraception