Genotype and Platelet Reactivity in Patients on Hemodialysis
Status:
Unknown status
Trial end date:
2015-08-01
Target enrollment:
Participant gender:
Summary
Patients with end stage renal disease (ESRD) on hemodialysis (HD) exhibited higher platelet
reactivity to clopidogrel than did those with normal renal function. We recently reported
platelet inhibition by ticagrelor was faster and markedly greater than by clopidogrel with
onset dosing regimen in patients with ESRD on HD. However, few studies have been conducted
genetic influence in high platelet reactivity in patients with ESRD on HD.