Overview

Genotype-directed Neoadjuvant Chemoradiation for Rectal Carcinoma

Status:
Completed
Trial end date:
2010-08-01
Target enrollment:
Participant gender:
Summary
Determine if genotype-directed neoadjuvant chemoradiation, using information from the thymidylate synthase promoter polymorphism, result in a greater degree of tumor downstaging in high risk patients compared to historical controls.
Phase:
Phase 2
Details
Lead Sponsor:
Washington University School of Medicine
Treatments:
Fluorouracil
Irinotecan