Recurrent UTIs are common among patients on IC. These create significant patient morbidity
and healthcare burden. In desperation, many physicians prescribe prophylactic oral or
intravesical antibiotics. This practice is common among our Gillette clinic patients.
However, the benefit is unclear and the risks are not insignificant. As such, practice
variation is significant. In order to better define the evidence for or against gentamicin
bladder irrigation and thus inform clinical practice both locally at our Gillette urology
clinic and for practitioners at large we will pursue the following specific aims:
1. Compare rates of symptomatic urinary tract infection and asymptomatic bacteriuria among
a population of Gillette patients on IC with and without gentamicin bladder
instillation.
2. Compare antibiotic resistance rates among a population of Gillette patients on IC with
and without gentamicin bladder instillation.