Gentamicin Versus Clindamycin Versus Normal Saline Lavage in Axilla

• Status: Completed
• Trial end date: 2014-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

The patients undergoing axillary lymph node dissection were randomized into 3 groups:

patients undergoing lavages with normal saline (Group 1), patients undergoing lavage gentamicin solution (Group 2) and patients undergoing lavage with a clindamycin solution (Group 3). Drainage volume discharge is investigated

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospital General Universitario Elche
• Treatments: Clindamycin; Clindamycin palmitate; Clindamycin phosphate; Gentamicins; Pharmaceutical Solutions

Criteria

Inclusion Criteria:

• diagnosis of breast neoplasms

• plans to undergo an elective ALND of Berg's levels I and II due to axillary metastasis determined preoperatively by core biopsy or evidence of metastasis in the SLNB in the intraoperative or in the differed analysis.

Exclusion Criteria:

• allergy to any of the antibiotic drugs used

• chronic renal failure due to possible toxicity of gentamicin

• patients undergoing a modified radical mastectomy.