Overview

Geriatric Ketamine for Pain Management Study

Status:
Completed
Trial end date:
2018-04-01
Target enrollment:
0
Participant gender:
All
Summary
This research project is geared towards geriatric analgesia in the Emergency Department (ED) with a goal of reducing the administration of opioid pain medications to elderly patients, thereby avoiding the commonly occurring, severe side effects associated with such medications, including hypotension, respiratory depression, altered mental status, delirium, as well as nausea/vomiting and constipation. The primary outcome of the study will be difference in pain score from baseline to 30 minutes post-medication administration. This project has the potential to change and modify the ED approach to geriatric analgesia by virtue of minimizing the use of opioid administration in elderly patients. T
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Antonios Likourezos
Treatments:
Ketamine
Morphine
Criteria
Inclusion Criteria:

- ED patients; 65 years of age and older; abdominal, flank, back, traumatic chest, neck
or musculoskeletal pain; capacity to give verbal or written consent.

Exclusion Criteria:

- ED patients <65 years old; altered mental status; presenting with headache,
non-traumatic chest pain; allergy to morphine or ketamine; weight <40kg or >115kg,
unstable vital signs (systolic blood pressure <90 or >180 mmHg; heart rate <5 or >150
beats per minute; and respirations <8 or >30 per minute), and past medical history of
severe renal or hepatic insufficiency, alcohol or drug abuse or psychiatric illness;
Patients with BMI>40; severe COPD