German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (06/99)
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The study evaluates the efficacy and tolerability of an intensified induction and
consolidation therapy. Thereafter patients receive individualised treatment stratified
according to relapse risk with stem cell transplantation for patients with high and very high
risk of relapse. Patients with standard risk receive further consolidation and reinduction
chemotherapy. In parallel minimal residual disease (MRD) is evaluated. A MRD based risk
stratification and treatment decision is developed.