German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003)
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The study evaluates the efficacy and tolerability of an intensified induction and
consolidation therapy. Thereafter patients receive individualised treatment stratified
according to relapse risk with stem cell transplantation for patients with high and very high
risk of relapse. Patients with standard risk receive further consolidation and reinduction
chemotherapy. In parallel minimal residual disease (MRD) is evaluated. After six months and
one year the decision on intensification or discontinuation of therapy is made based on the
results of MRD evaluation.
Phase:
Phase 4
Details
Lead Sponsor:
Johann Wolfgang Goethe University Hospital
Collaborators:
Deutsche Krebshilfe e.V., Bonn (Germany) German Federal Ministry of Education and Research