Getting Biased Treatment Study: How Psychotherapy and Antidepressants Change Brain Activity in Chronic Depression

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine how psychotherapy and pharmacotherapy respectively change brain activity in patients suffering from chronic depression.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Charite University, Berlin, Germany
• Collaborator: German Federal Ministry of Education and Research
• Treatments: Antidepressive Agents; Duloxetine Hydrochloride

Criteria

Inclusion Criteria:

• Chronic Depression (Double Depression, Chronic MDE, MDE with incomplete remission)

• HAMD-24>20

Exclusion Criteria:

• Concurrent Psychotherapy or Psychopharmacotherapy

• Previous Non-Response to Duloxetine

• Non-Response to three Antidepressants of two different groups given at adequate doses or Non-Response to two empirically tested forms of Psychotherapy in the current Depressive Episode

• Serious Psychiatric comorbidity

• Serious Neurologic comorbidity

• Contraindications to Duloxetine

• Contraindications to fMRI