Ghrelin Plus Strength Training in Frail Elderly Study
Status:
Completed
Trial end date:
2016-08-31
Target enrollment:
Participant gender:
Summary
Frailty is a geriatric syndrome leading to physical deterioration including muscle wasting
(sarcopenia) and unintentional weight loss. There are currently no approved therapies for
frailty. Ghrelin is a hormone produced by the stomach that stimulates appetite centers in the
brain. The investigators already know that a single dose of Ghrelin improves food intake
immediately after the dose in frail older people. In addition, exercise programs have been
shown to improve strength and function in older people. In this study, the investigators are
trying to find out if a joint intervention of ghrelin and resistance training will improve
walking, balance and leg strength in frail elderly people.