Hyperglycemia increases the risk of complications in surgical patients. Focus on poor
glycemic control as a contributor to adverse outcomes in settings outside the intensive care
unit (ICU) is often dismissed. Total parenteral Nutrition (TPN) has been used in providing
surgical patients with nutrition to prevent deterioration of nutritional status. However,
many diabetic patients receiving TPN develop exaggerated hyperglycemia that requires frequent
insulin administration via sliding scale. Providing diabetic patient's receiving TPN basal
insulin is a known strategy to aid in blood sugar control and prevention of high blood sugar
spikes. Many strategies for basal insulin provision have been utilized clinically during the
administration of TPN; this includes the incorporation of insulin with TPN solution or
administration of long acting insulin such as glargine. However, no study has compared any of
these strategies aiming for selecting the optimum modality for controlling blood glucose in
diabetic surgical patient's receiving TPN. We will conduct a study to compare the efficacy of
once daily insulin glargine versus continuous regular insulin incorporated TPN in controlling
blood glucose in non-critically ill diabetic surgical patients receiving TPN.