Glucocorticoids With Antihistamines Versus Antihistamines in Acute Urticaria in Emergency

• Status: Completed
• Trial end date: 2014-02-01
• Target enrollment: 0
• Participant gender: All

Summary

Acute urticaria is common and affected 12% of population. 400 patients come in department emergency of Toulouse each year and there aren't many studies in literature which evaluate the glucocorticoids treatment. The standard treatment of urticaria is antihistamines H1, but glucocorticoids treatment administered orally for short course would permit to increase quickly acute urticaria uncomplicated. Clinical trial, prospective randomized double blinded of adults with acute urticaria less 24 hours duration and no take treatment urticaria before.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Toulouse
• Treatments: Glucocorticoids; Histamine Antagonists; Histamine H1 Antagonists; Prednisone

Criteria

Inclusion Criteria:

• adults

• urticaria rash no more 24 h duration and no take treatment for urticaria

Exclusion Criteria:

• patients were presented severe anaphylaxis or taken antihistamines or glucocorticoids within 5 days of arrival at ED,

• severe infection

• pregnancy

• patients BPCO

• diabetics

• allergy corticosteroids

• refusal to comply

• participate an other study