Glucocorticoids for Post-operative Patients With Acute Type A Aortic Dissection (The GLAD Trial)
Status:
Not yet recruiting
Trial end date:
2024-06-30
Target enrollment:
Participant gender:
Summary
This study is designed to evaluate the effects of glucocorticoid(GC) on improving
post-operative organ dysfunction in patients with acute type A aortic dissection. Eligible
patients will be randomly assigned on a 1:1 ratio to the GC group and the control group.
Patients in the GC group will receive intravenous methylprednisolone from post-operative day
1 to post-operative day 3, while those in the control group will follow standard treatments.
The primary outcome is the area under the curve of SOFA score from baseline(pre-operative) to
post-operative day 3.