Glucose Control With Multiple Daily Insulin Injections In Diabetic Patients Hospitalized In A General Medicine Ward
Status:
Terminated
Trial end date:
2006-09-01
Target enrollment:
Participant gender:
Summary
At least 20% of patients hospitalized in the general medical and surgical wards at any given
time suffer from diabetes. It has been demonstrated that poor clinical outcome correlates
with the degree of hyperglycemia in these patients. Strict glucose control in hospitalized
patients improves clinical outcomes in the setting of acute myocardial infarction, cardiac
surgical procedures, infection and critical illness in patients hospitalized in intensive
care units if insulin is applied intravenously. It is, however, complex to obtain strict
glucose control in the general surgical and medical wards. These wards are usually
understaffed as compared to intensive care units and therefore are incapable to perform the
necessary close monitoring essential in patients treated with intravenous insulin. We intend
to test the feasibility of glucose control by multiple daily subcutaneous injections with
long acting basal glargine insulin and pre-meal insulin analogues. If good glucose control
can be achieved, this would be a valid, more convenient and acceptable alternative to
intravenous insulin infusions to obtain good glucose control in diabetic patients
hospitalized in general internal medicine wards.