Glutathione vs. Curcumin Clinical Trial

• Status: Recruiting
• Trial end date: 2020-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The investigator proposes to perform a phase I/II study comparing two nutraceuticals and placebo that target mediators identified in the investigator's prior dynamic modeling study of Gulf War Illness (GWI). The investigator will repeat the dynamic modeling before treatment and on therapy to assess the modeling and the impact of the interventions on the homeostatic networks that have identified, with an added focus on the glutathione/redox system.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: South Florida Veterans Affairs Foundation for Research and Education
• Treatments: Curcumin

Criteria

Inclusion Criteria:

• Veterans with Gulf War Illness

• 35 to 70 years old

• Good health by medical history prior to 1990

• Currently have no exclusionary diagnoses that could reasonably explain the symptoms of their fatiguing illness and their severity

Exclusion Criteria:

• Major depression with psychotic or melancholic features

• Schizophrenia

• Bipolar disorder

• Delusional disorders

• Dementias of any type

• History or current alcohol abuse

• History or current drug abuse

• Current tobacco use

• Organ failure

• Defined rheumatologic

• Inflammatory disorders

• HIV

• Hepatitis B and C

• Primary sleep disorders

• Steroids

• Immunosuppressives