Glyburide vs Glucovance in the Treatment of GDM

• Status: Terminated
• Trial end date: 2018-08-14
• Target enrollment: 0
• Participant gender: Female

Summary

A randomized comparison of glyburide to glucovance (metformin -glyburide) in the management of diabetes in pregnancy.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Texas Tech University Health Sciences Center, El Paso
• Treatments: Glyburide; Metformin

Criteria

Inclusion Criteria:

• Gestational diabetes

• Pregnancy > 12 weeks gestation

• Ability to give consent

Exclusion Criteria:

• Inability to consent to the study

• Pre-existing diabetes

• Glucose-6-phosphate dehydrogenase (G6PD) deficiency

• Serum creatinine >1

• Liver disease

• Allergy to sulfa;

• Allergy to glyburide;

• Allergy to metformin;

• Fetal anomalies