Glycemic Control and Variability for Congestive Heart Failure Exacerbation

• Status: Completed
• Trial end date: 2013-09-01
• Target enrollment: 0
• Participant gender: All

Summary

High glucose as well as fluctuations (rapid swings) in blood glucose can contribute to severe hospital complications and even death.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Kathleen Dungan
• Collaborator: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Treatments: Insulin; Insulin, Globin Zinc

Criteria

Inclusion Criteria:

• Age 18 and above

• Admitted (less than 48 hours) to the with worsening heart failure

• Hyperglycemia or diabetes. Hyperglycemia is defined as blood glucose greater than 150 mg/dL on at least 2 occasions separated by at least 4 hours apart, insulin use, or HbA1c >6.5%.

Exclusion Criteria:

• Type 1 diabetes

• Receiving comfort care measures only

• Hospital stay expected to be less than 2 days

• Pregnancy

• Prisoners

• Participation in the study on prior hospitalizations

• Acute myocardial infarction within 3 months

• End stage renal or liver disease