Gradual Withdrawal of Remifentanil Infusion Reduced Postoperative Pain and Opioid Requirement During Breast Surgery
Status:
Completed
Trial end date:
2019-07-03
Target enrollment:
Participant gender:
Summary
Although remifentanil provides profound analgesia during operation, postoperative occurrence
of hyperalgesia and tolerance after remifentanil administration could be a challenge to the
postoperative pain control. Evaluation of analgesia and anti-nociception during anesthesia is
still a challenging issue. Surgical Pleth Index (SPI) is a non-invasive and simple access
tool used to monitor autonomous nervous system during anesthesia. This technique is based on
photoplethysmographic wave and heart beat analysis. SPI values range between 0 (no stress)
and 100 (high stress level). The purpose of this study was to determine the appropriate use
of Remifentanil for pain control in patients with SPI.