Overview

Grass Pollen Immunotherapy Plus Dupilumab for Tolerance Induction

Status:
Recruiting
Trial end date:
2025-01-01
Target enrollment:
Participant gender:
Summary
The primary objective of this study is to assess whether the combination of grass allergen sublingual immunotherapy (SLIT) and dupilumab for 2 years is more effective than double placebo in suppressing the nasal allergen challenge (NAC) response to grass pollen at 1 year after completion of study medication.
Phase:
Phase 2
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborators:
ALK-Abelló A/S
Immune Tolerance Network (ITN)
PPD
Regeneron Pharmaceuticals
Rho Federal Systems Division, Inc.
Treatments:
Antibodies, Monoclonal
Immunologic Factors