Group A Pharyngitis in Children: The GASPARD Study

• Status: Unknown status
• Trial end date: 2018-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Evaluate the necessity to treat with antibiotics GAS pharyngitis in children in Switzerland. The null hypothesis is that antibiotic treatment is not necessary for GAS pharyngitis in this population.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Klara Posfay-Barbe
• Collaborators: Gertrude Von Meissner Foundation; Recherche et Développement des HUG; Société académique de Genève
• Treatments: Amoxicillin

Criteria

Inclusion Criteria:

• 3 -15 years old

• Clinical symptoms suggestive of pharyngitis with MC Isaac score ≥3

• Rapid-antigen detection test (RADT) positive for GAS-

• Signed informed parental/patient consent form

Exclusion Criteria:

• Hypersensitivity to B-lactams

• concomitant disease which must be treated with antibiotics

• chronic disease-Immunocompromised

• Antibiotics within 72 h

• history of ARF,scarlet fever,impetigo,acute glomerulonephritis

• Family history of ARF

• Complicated pharyngitis