Gut Hormones in Obesity, Nicotine and Alcohol Dependence
Status:
Active, not recruiting
Trial end date:
2020-08-01
Target enrollment:
Participant gender:
Summary
The "Gut Hormones in Addiction" study is a proof-of-concept experimental medicine human study
to answer the following questions:
1. Does the administration of the hormone desacyl ghrelin reduce core behavioural
components of addiction in dependent individuals who have recently stopped smoking
tobacco or drinking alcohol, or overweight/obese subjects?
2. Does the administration of the drug Exenatide reduce core behavioural components of
addiction in dependent individuals who have recently stopped smoking tobacco or drinking
alcohol, or overweight/obese subjects?
3. Does the administration of desacyl ghrelin or Exenatide reduce reward responses to
high-calorie foods and appetite in dependent individuals who have recently stopped
smoking tobacco or drinking alcohol, or overweight/obese subjects?