Overview

Gut Microbiota Reconstruction for NSCLC Immunotherapy

Status:
Not yet recruiting
Trial end date:
2022-12-30
Target enrollment:
Participant gender:
Summary
In this study, patients with locally advanced or metastatic NSCLC after first-line treatment with PD-1/PDL-1 monoclonal antibody will be treated with Gut Microbiota reconstruction(such as FMT) combined with PD-1/PDL-1 monoclonal antibody. We will evaluate the safety of FMT in the treatment of advanced NSCLC, and analyze the effect of FMT on intestinal flora and immunophenotype of patients.
Phase:
Phase 1
Details
Lead Sponsor:
Shanghai Zhongshan Hospital
Treatments:
Antibodies
Antibodies, Monoclonal
Durvalumab
Nivolumab
Pembrolizumab