Primary objective: Compare Pegasys RGT overall response rate (i.e., HBeAg seroconversion
rate) with Pegasys mono historical response rate at week 72 (48 week treatment with 24 week
follow up)
Secondary objective :
- The changes of HBsAg titer
- The rate of combined HBeAg seroconversion and HBV DNA < 300 copies/mL
- The rate of serum HBV DNA < 300 copies/mL ⅳ. The rate of ALT normalization
- The rate of HBsAg loss ⅵ. The rate of serum HBV DNA < 10,000 copies/mL